The world ofOne Pieceis filled with powerful organizations that are always trying to get the better of one another. Due to the constant power struggle that they are involved in, most of these groups end up being destroyed or are forced to cease their activities.

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One such institution that existed decades ago wasMADS, and it was active before the current timeline. MADS was an illegal scientific group that was headed by five distinct scientists. Obviously, the group needed money to work, and it was provided by Du Feld, a prominent figure in theOne PieceUnderworld. The identities of the members of MADS remained a secret for a long time, but they were finally revealed in the Egghead Island arc.

5Caesar

Caesar was introduced in the Punk Hazard arc, and he servedas its main villain. He is a mad scientist who worked for Big Mom and Kaido, two of the most notorious pirates in the world. Caesar’s modus operandi was vile, and he didn’t care about who was harmed in his experiments. Time and time again, Caesar has proven that he does not have any moral fiber. In the Punk Hazard arc, it was revealed that Caesar operated on kids to accomplish his goal of gigantification. Thankfully, he was stopped by Luffy.

Sometime after MADS was dissolved, Caesar started working with Vegapunk for the World Government, but it didn’t take long for the evil scientist to start constructing a weapon that was both illegal and dangerous. When Vegapunk caught him, Caesar set off the weapon that resulted in the deaths of many people. In the recent cover stories, Caesar was seen helping the Vinsmoke kids escape Big Mom’s territory, and it was later confirmed that he had left with them.

One Piece Caesar Clown In His Half Gaseous Form

4Stussy

Stussy isa member of CP0. She made her debut in the Whole Cake Island arc, where she was introduced as one of the members of the Underworld. Later on, it was revealed that Stussy is a highly talented assassin, who has worked on many covert operations for the World Government.

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Surprisingly, before becoming a Cipher Pol agent, Stussy used to be a member of MADS. This was revealed in the Egghead Island arc. When CP0 arrived at Egghead Island to kill Vegapunk and his bodies, Stussy was able to explain all the defense systems that Vegapunk had placed all over the place. This incident put her under suspicion, which was confirmed in Chapter 1070 when she was featured on the cover story alongside the other four leading members of MADS. The revelation about Stussy being a member of the group raises the question of how she has managed to stay young while the others have aged.

3Queen

Queen is one of the All-Stars, which makes him one of the strongest fighters of the Beasts Pirates. He is a ruthless man who likes to toy with his opponent before finishing them off. Queen possesses theRyu Ryu no Mi, Model: Brachiosaurus, an Ancient Zoan-type devil fruit. It allows Queen to transform into the prehistoric beast, bolstering his physical power significantly.

He might not look like it, but Queen used to be a member of MADS. Due to his intelligence, Queen is able to create weapons such as deadly diseases that can annihilate large groups of people easily. He even modified parts of his body to help him fight better. Despite his impressive arsenal, Queen was defeated easily by Sanji in the Wano Country arc.

Stussy a member of CP0

2Vinsmoke Judge

Vinsmoke Judge is the patriarch of the Vinsmoke Family and a former member of MADS. Like Caesar, Judge falls into the category of an evil scientist. During his time with MADS, Judge managed to figure out how the Lineage Factor worked. He used the findings to modify his own children to give them limitless power. Judge’s genius didn’t stop there; he created clones of his kids, and he also began manufacturing soldiers. With the combined power of his kids and soldiers, Judge was able to take over entire kingdoms.

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Queen in One Piece anime

Judge also created the Raid Suits, which are remarkable inventions that allow his children to fight in an even more effective manner. His thirst for power nearly cost him and his family their lives, but they were saved by Sanji. After the events of the Whole Cake Island arc, Judge and Germa Kingdom lost their privileges, includingtheir status as royalty, and they became targets for the World Government.

1Dr. Vegapunk

Dr. Vegapunk isthe smartest character in the series. His name was brought up many times after the time skip, but he didn’t make an appearance until the Egghead Island arc. Vegapunk possesses the Nomi Nomi no Mi, which is a Paramecia-type devil fruit. It allows him to store all the information he has ever learned. However, in order to store it, his brain and head keep increasing in size. This effectively makes him the person with the biggest brain in the world.

Over 20 years ago, Vegapunk worked alongside four other members of MADS. The group managed to make a name for itself, which prompted the World Government to take action. Since siding with the Marines, Vegapunk has been responsible for creating some of the most notable inventions in the series, like the Pacifista, a copy of Kaido’s devil fruit, etc. However, his best creations are the Seraphim. According to Vegapunk, the Seraphim are the strongest beings on the sea. The Seraphim possess Lunarian traits that grant them extra strength and speed. Furthermore, they are armed with different devil fruits that suit their fighting style. Vegapunk has programmed them in such a way that they manage to improve after every fight.

Vinsmoke Judge leader of Germa 66

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Vegapunk One Piece 1074