2021 produced plenty of greatanimeacross a wide spectrum of genres. Action fans were treated toTokyo Revengers,Attack on Titan: The Final Season,World Trigger,JoJo’s Bizarre Adventure: Stone Ocean,Demon Slayer, andNomad: Megalo Box 2. The year also produced a healthy array of drama series, withFruits Basket: The Final,Link Click,To Your Eternity, and86ranking among the greatest anime of 2021.RELATED:Best Anime MoviesNaturally, the year’s seasons were also not lacking in hilarious shows. While many anime incorporate humor as one ingredient in a much larger recipe, some series push comedy to the forefront, setting out specifically to encourage endless giggles in their audiences. These are thebest comedy anime series of 2021.Updated August 05, 2025 by Mark Sammut: The Winter 2022 anime season is well underway, and a couple of noteworthy comedies are airing such as Teasing Master Takagi-san season 3 and Life with an Ordinary Guy Who Reincarnated into a Total Fantasy Knockout. However, there can never be enough laughter in the world, so while waiting for new episodes to drop, fans might want to catch up on some 2021 series that they had missed. Therefore, this article has been expanded to include a few more of thebest comedy anime of 2021.Honorable mentions:Obey Me!,Bungou Stray Dogs Wan!,SK8 the Infinity,Taishou Maiden Fairytale, andThe Slime Diaries: That Time I Got Reincarnated as a Slimeââ.Pui Pui Molcaris also all sorts of adorable.
Where to Stream
Funimation
Through his capitalist expertise, Kinji Ninomiya finally achieves his dream of a carefree life that sustains itself. Unfortunately, he gets teleported to a fantasy world and has to start from scratch. Not wavering in confidence, Ninomiya sets out to dominate this world, facing every challenge head-on and without a hint of doubt.
While its scatterbrain plot leaves a lot to be desired,The Dungeon of Black Companygets its comedy spot-on. Ninomiya is a fantastic lead, and the anime uses its setting to comment on workplace culture.
Hulu,Funimation
Love is unpredictable. The seemingly perfect Kyouko Hori and the reserved Izumi Miyamura act very differently outside of school, and they end up striking a charming relationship when they see each other’s real selves.
RELATED:Romance Anime To Watch If You Love My Dress-Up Darling
A romcom with slice of life elements,Horimiyadelivers its biggest laughs during its opening episodes as Kyouko and Izumi’s banter often manages to be both hilarious and sweet. The anime does lose momentum towards the end, although it can still produce the occasional giggle.
Funimation,Crunchyroll,VRV
If someone found the first season ofZombieland Sagato be a laugh riot, then the sequel should not disappoint. Along with greatly improving its concert sequences,Revengedoubles down on the strong personalities of its characters. Somehow, the anime found a way to make Koutarou Tatsumi even funnier than he was in the original season, which is saying something.
Zombieland Saga Revengedoes not always prioritize humor, as theidol animehas a fair amount of drama as well, however, when the show tries to be funny, it usually succeeds.
Netflix
Split into two short cours,The Way of the Househusbandis aNetflix seriesrevolving around an ex-yakuza boss who has decided to become a stay-at-home husband. The anime milks this premise for all it’s worth, frequently using Tatsu’s intensity to spark misunderstandings with everyone who happens to cross his path.
Gokushufudou’s static animation style does take some getting used to, but J.C. Staff uses it to good comedic effect. While the anime does get a bit repetitive as most of the humor is built upon the same punchline,The Way of the Househusbandis nevertheless a fun and quick watch.
An office comedy with quite a bit of romance,My Senpai is Annoyingfollows Futaba Igarashi, a junior saleswoman who is partnered with an enthusiastic senior coworker, Harumi Takeda. The show bases its comedy on the obvious romantic tension that exists between the characters, some of whom are oblivious while others struggle to accept their own feelings.
RELATED:Anime: Best Pilot Episodes Of The Fall 2021 Season
My Senpai is Annoying’s succeeds due to the likability of its characters, all of whom feel grounded in a semblance of reality as they face relatable hurdles at work. Futaba is the star of the show here, as her reactions carry the majority of the humor.
5-toubun no Hanayome â¬
Crunchyroll,Funimation
One of the best harem anime of 2021,The Quintessential Quintuplets 2also produced some of the biggest laughs of the year, particularly during its earliest episodes. Fuutarou Uesugi’s quest to tutor the Nakano quintuplets so they get passing grades continues to hit one roadblock after another, leading to arguments, surprise appearances by figures from the protagonist’s past, and the occasional need to put on a wig.
The Quintessential Quintuplets 2doesn’t focus solely on comedy and spends a significant amount of time exploring the characters' relationships, but whenever the anime tries a joke, it nearly always lands.
Life Lessons With Uramichi-Oniisanhas a classic comedic premise: what if the performers of a children’s show were the complete opposite of the happy-go-lucky characters they portray? On “Together with Maman,” Uramichi Omota pretends to be an energetic and positive person, a facade that (barely) masks his jaded and bitter personality.
Life Lessons With Uramichi-Oniisanplays open this juxtaposition brilliantly, and the anime complements Uramichi’s aggressive disinterest with secondary characters who are also far from pleased with their current situations.
Crunchyroll,VRV
2021 was very kind when it came to anime sequels, andWelcome to Demon School! Iruma-kun Season 2more than lived up to its entertaining predecessor. A human adopted by a demon and sent to a school that regularly sings about eating mortal, Iruma has gone from fearing for his life to genuinely enjoying his time in hell.
RELATED:Best Shonen Manga That Started In 2021
Season 2 highlights the strength of the anime’s supporting characters; while the original season predominantly focuses on Iruma, Clara, Alice, and Ameri, the sequel allows the rest of Babyls School’s misfits to shine a bit more brightly. Alice and Clara were also one of the year’s best double acts, constantly producing comedy gold.
Perhaps the most controversial placement on this list,Girlfriend, Girlfriendis an unapologetically stupid show. Naoya Mukai is such an honest person that he simply cannot get himself to reject the cute Nagisa Minase despite already having a girlfriend, Saki, whom he cares deeply about. Therefore, Naoya proposes that he dates both of them and, somehow, convinces Nagisa and Saki to go along with it.
As long as somebody does not take it too seriously,Girlfriend, Girlfriendis an entertaining parody of harem and romance anime. An honorable two-timing protagonist, Naoya is a breath of fresh air in a genre that tends to over-rely on oblivious or weak-willed main characters. The girls are also pretty decent, especially Saki, a character who is Naoya’s comedic equal.
Crunchyroll,VRV,HIDIVE
Non Non Biyorihas been anincredible slice of life animesince its first episode, however, it didn’t transform into a fantastic comedy anime untilNonstop. While the previous seasons have their funny moments,Nonstoptook those beats that worked and amplified them, creating a far more consistent experience.
Non Non Biyori Nonstopstill revolves primarily around the four girls attending Asahigaoka’s school, all of which are charming and capable of laugh-out-loud moments. What sets this season apart from its predecessors is that it makes more frequent and better use of the show’s supporting characters, who all complement the main girls splendidly.
